LARGER VIALS = LARGER SAVINGS PER mg

L-Carnitine

L-Carnitine

$60.00
$60.00
SAVE Liquid error (snippets/price line 116): Computation results in '-Infinity'% Sold out

science Lab-Tested 99% Purity

local_shipping Fast, Discreet Shipping

school For Research Use Only

 
add_shopping_cart

-

Ordered

local_shipping

- - -

Order Ready

redeem

- - -

Delivered

L-Carnitine

L-Carnitine

$60.00
$60.00
SAVE Liquid error (snippets/price line 116): Computation results in '-Infinity'% Sold out

L-Carnitine is a naturally occurring amino acid derivative that facilitates the transport of long-chain fatty acids into mitochondria for β-oxidation. It is being studied for its potential roles in enhancing energy metabolism, improving exercise performance, and supporting cardiovascular health.

View full details
  • DESCRIPTION
  • STORAGE
  • REFERENCES

L-Carnitine is a naturally occurring quaternary ammonium compound synthesized from lysine and methionine. It plays a key role in fatty acid transport into mitochondria, enabling β-oxidation and energy production. L-Carnitine and its derivatives (acetyl-L-carnitine, propionyl-L-carnitine) are extensively studied for roles in metabolism, cardiovascular health, exercise performance, and neuroprotection.

Structure

  • Chemical Formula: C₇H₁₅NO₃
  • Molecular Weight: ~161 Da
  • Form: Water-soluble, zwitterionic molecule
  • Mechanism: Facilitates long-chain fatty acid transport into mitochondria for energy generation

Research

Metabolism & Energy Production

  • Critical for fatty acid oxidation, transporting long-chain fatty acids across the inner mitochondrial membrane.
  • Enhances mitochondrial efficiency and energy output.

Exercise & Recovery

  • Supplementation is associated with reduced exercise-induced muscle damage, improved recovery, and enhanced endurance performance.
  • Increases utilization of fatty acids during prolonged exercise.

Cardiovascular Health

  • Propionyl-L-carnitine improves endothelial function and circulation in peripheral artery disease.
  • Shown to reduce angina symptoms and support heart function in ischemic models.

Neuroprotection

  • Acetyl-L-carnitine supports cognitive function, mitochondrial health, and neurotransmitter synthesis.
  • Studied for roles in Alzheimer’s disease, depression, and neuropathy.

Weight Management & Metabolic Disorders

  • Research suggests modest benefits in weight loss and insulin sensitivity.
  • Used in studies of type 2 diabetes, obesity, and metabolic syndrome.

Safety Profile

  • Generally safe and well tolerated.
  • High doses may cause mild gastrointestinal upset or fishy odor (from TMA production).

Summary

L-Carnitine is an essential mitochondrial cofactor that supports fat metabolism, cardiovascular function, exercise recovery, and neuroprotection. Research highlights include:

  • Fatty acid transport and energy production
  • Benefits in exercise recovery and endurance
  • Applications in cardiovascular and metabolic health
  • Neuroprotective roles via acetyl-L-carnitine

This product is supplied as a lyophilized powder or solution depending on formulation. Store at 2–8 °C, protected from light and moisture. For long-term preservation, keep unopened vials at −20 °C. After reconstitution (if lyophilized), prepare under sterile conditions, refrigerate at 2–8 °C, and use promptly. Avoid repeated freeze–thaw cycles.

1. Bremer J. Carnitine—metabolism and functions. *Physiol Rev*. 1983;63(4):1420–1480. doi:10.1152/physrev.1983.63.4.1420

2. Rebouche CJ, Seim H. Carnitine metabolism and its regulation in microorganisms and mammals. *Annu Rev Nutr*. 1998;18:39–61. doi:10.1146/annurev.nutr.18.1.39

3. Brass EP. Supplemental carnitine and exercise. *Am J Clin Nutr*. 2000;72(2 Suppl):618S–623S. doi:10.1093/ajcn/72.2.618S

4. Wall BT, et al. L-Carnitine supplementation increases skeletal muscle carnitine content and alters muscle fuel metabolism in humans. *J Physiol*. 2011;589(Pt 4):963–973. doi:10.1113/jphysiol.2010.201343

5. Hiatt WR, et al. Carnitine and peripheral arterial disease: clinical trial evidence. *J Am Coll Cardiol*. 1995;26(5):1199–1204. doi:10.1016/0735-1097(95)00306-6

6. Malaguarnera M, et al. L-Carnitine supplementation reduces oxidative stress in type 2 diabetes patients. *Diabetes Metab*. 2009;35(6):447–454. doi:10.1016/j.diabet.2009.05.001

7. Montgomery SA, et al. Acetyl-L-carnitine in the treatment of depression. *Int Clin Psychopharmacol*. 2003;18(1):45–49. doi:10.1097/00004850-200301000-00007

8. Pettegrew JW, et al. Clinical and neurochemical effects of acetyl-L-carnitine in Alzheimer’s disease. *Neurobiol Aging*. 1995;16(1):1–4. doi:10.1016/0197-4580(95)80001-8

9. Galloway SDR, et al. Effects of carnitine supplementation on exercise performance and recovery. *J Sports Sci*. 2004;22(9):855–866. doi:10.1080/02640410410001716739

10. Flanagan JL, et al. L-Carnitine and acetyl-L-carnitine in the treatment of metabolic disease and aging. *Ann N Y Acad Sci*. 2010;1205:87–95. doi:10.1111/j.1749-6632.2010.05656.x